Clinical Associate Professor
B.S. University of Illinois at Urbana-Champaign, Molecular Genetics/Plant Biotechnology
Ph.D. University of California Davis, Genetics
Post-doc University of Maryland School of Medicine, Genetic Etiology of Complex
Traits
General biology
Genetics (molecular and developmental)
Biotechnology
Model organisms (zebrafish and chick)
Biology is the foundation for life. As such, an understanding of this branch of science is important for helping health care professionals best protect the lives of their patients by making connections between symptoms and the biological causes. My lifelong passion for teaching and deep-rooted interests in the genetics of human diseases and developmental disorders has uniquely prepared me to teach biology and its relevance to human health and medicine. In the classroom I aim to help students better understand biology and the role it plays in the human body and the larger world in which they live through the utilization of different learning styles as well as classroom and laboratory activities – all of which are designed to best engage and train students to become active learners both inside and outside the classroom.
O’Hare, E.A., Antin, P.B., and Delany, M.E. 2019. Two Proximally-Close Priority Candidate Genes for diplopodia-1, an Autosomal Inherited Craniofacial-Limb Syndrome in the Chicken: MRE11 and GPR83. Journal of Heredity. 110(2):194-210. PMID: 30597046.
Montasser, M.E.*, O’Hare, E.A.*, Wang, X., Howard, A., McFarland, R., Perry, J.A., Ryan, K.A., TopMED, Shuldiner, A.R., Miller, M., Mitchell, B.D., Zaghloul, N.A., Chang, Y-P.C. 2018. An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels. Circulation. 30(4):429-445. PMID: 29593015. *Co-first authors are listed in alphabetical order.
Webb, A.E., Youngworth, I.A., Kaya, M., Gitter, C.L., O’Hare, E.A., May, B.P., Cheng, H.H., Delany, M.E. 2018. Narrowing the region containing the single gene mutation wingless-2 on chicken chromosome 12. Poultry Science. 97(6):1872-1880. PMID: 29562287.
O’Hare, E.A., Yang, R., Yerges-Armstrong, L., Sreenivansan, U., McFarland, R., Leitch, C. C., Wilson, M. H., Narina, S., Gorden, A., Ryan, K., Shuldiner A.R., Farber, S. A., Wood, G.C., Still, C.D., Gerhard, G.S., Robishaw, J.D., Sztalryd, C., Zaghloul, N.A. 2017. TM6SF2 rs58542926 impacts lipid processing in liver and small intestine. Hepatology. 65(5):1526-1542. PMID: 28027591.
O’Hare, E.A., Yerges-Armstrong, L.M., Perry, J.A., Shuldiner, A.R., and Zaghloul,
N.A. 2016. Assignment of functional relevance to genes at type 2 diabetes-associated
loci through investigation of β-cell mass deficits. Molecular Endocrinology. 30(4):429-445.
PMID: 26963759.
Lodh, S., Hostelley, T.L.*, Leitch, C.C.*, O’Hare, E.A.*, Zaghloul, N.A. 2016. Differential effects on β-cell mass by disruption of Bardet-Biedl Syndrome or Alstrom Syndrome genes. Human Molecular Genetics. 25(1):57-68. PMID: 26494903. *Secondary authors are listed in alphabetical order.
Schmidt, M., Smith, J., Burt, D.W, Aken, B.L., Antin, P.B., Archibald, A.L., Ashwell, C., Blackshear, P.J., Boshiero, C., Brown, C.T., Burgess, S.C., Cheng, H.H., … Delany, M.E., … O’Hare, E.A., … Zhou, H. 2015. “Treasure the Exceptions: Utilizing Chicken Mutant Lines and Advanced Genetic Technologies to Uncover Genes Involved in Developmental Processes” (O’Hare, E.A. and Delany, M.E) (pp. 137-141) in: Third report on chicken genes and chromosomes 2015. Cytogenetic and Genome Research. 145(2):1-103. PMID: 26282327.
O’Hare, E.A., Wang, X., Montasser, M.E., Chang, Y-P.C., Mitchell, B.D., and Zaghloul, N.A. 2014. Disruption of ldlr causes increased LDL-cholesterol and vascular lipid accumulation in a zebrafish model of hypercholesterolemia. Journal of Lipid Research. 55(11): 2242-2253. PMID: 25201834.
Chang, C.-F., Schock, E.N., O’Hare, E.A., Dodgson, J.B., Cheng, H.H., Muir, W.M., Edelman, R. E., Delany, M.E., and Brugmann, S.A. 2014. The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant, talpid2. Development. 141(15): 3003-3012. PMID: 25053433.
Lodh, S.*, O’Hare, E.A.*, Zaghloul, N.A. 2014. Primary cilia in pancreatic development and disease. Birth Defects Research Part C: Embryo Today: Reviews. 102(2): 139-158. PMID: 24864023. *Authors contributed equally to this work.
Robb, E.A., Antin, P.B., and Delany, M.E. 2013. Defining the sequence elements and candidate genes for the coloboma mutation. PLoS ONE. 8(4): e60267. PMCID: PMC3621764.
Robb E.A. and M.E. Delany. 2012. Case study of sequence capture enrichment technology: Identification of variation underpinning developmental syndromes in an amniote model. Genes. 3:233-247. PMID: 24704915.
Robb E.A. and M.E. Delany. 2012. The expression of pre-axial polydactyly is influenced by modifying genetic elements and is not maintained by chromosomal inversion in an avian biomedical model. Cytogenetic and Genome Research. 136:50–68. PMID: 22286052.
Robb E.A., Gitter, G.L., Cheng, H.H., and Delany, M.E. 2011. Chromosomal mapping and candidate gene discovery of chicken developmental mutants and genome-wide variation analysis of MHC-congenics. Journal of Heredity. 102(2):141-156. PMID: 21273214.
Swanberg S.E., O’Hare, T.H., Robb, E.A., Robinson, C.M., Chang, H., Delany, M.E. 2010. Telomere Biology of the Chicken: A Model for Aging Research. Experimental Gerontology. 45:647-654. PMID: 20399262.
Stekelenburg, C., Blouin, J-L., Santoni, F., Zaghloul, N.A., O’Hare, E.A., Dusaulcy, R., Maechler, R., and Schwitzgebel, V.M. 2022. Loss of Nexmif results in the expression of phenotypic variability and loss of genomic integrity. Scientific Reports. 12(1):13815. PMID: 35970867.
BIOL 191 Introductory Biology for Health Professions Lecture
BIOL 191L Introductory Biology for Health Professions Lab
BIOL 192 Introductory Biology for Health Professions Honors
BIOL 204 Educational and Career Planning for the Biologist
BIOL 415 Biotechnology
BIOL 614 Applied Biotechnology